What inspires you?
Do you want to contribute to cutting-edge research that can have a significant impact on the field of medicine and the world? If you think you have what it takes to pioneer advancements in chemistry, biochemistry, materials science, physics and biomedical engineering for the betterment of mankind, we would love to hear from you.
Please contact us to have a chat.
Open Positions
Senior Bioanalytical Chemist
Senior Chemical Engineer
Senior Mechanical Engineer
Senior Bioanalytical Chemist
Mobius Biomedical is an early-stage biopharmaceutical company that is focused on developing innovative, pathbreaking process technologies to dramatically reduce the costs of traditional biologics manufacturing.
Mobius Biomedical is searching for a qualified, highly motivated bioanalytical chemist to join our analytical team to perform characterization of biopharmaceutical products and serve as a Senior Bioanalytical Chemist. This position reports directly to the Chief Scientific Officer.
Primary Responsibilities
- Design experiments to develop methods for the characterization of biopharmaceutical products, including proteins and other biologic macromolecules, using spectrophotometric, chromatographic, and other analytical and bioanalytical instrumentation.
- Develop UV-Vis spectrometry, HPLC/UPLC, microplate reader, SEC, affinity chromatography, ion-exchange chromatography (IEX), hydrophobic interaction chromatography (HIC), circular dichroism, BCA assay, Bradford assay, ELISA, gel electrophoresis, SDS-PAGE, Wester Blot, Isoelectric focusing, ITC, SPR, and other bioanalytical methods.
- Work with interdisciplinary R&D teams to design and perform appropriate analytical experiments to advance process technology development.
- Work with the engineering and process development teams to develop methods for “in-process” and “in-line” testing.
- Design and execute method qualifications and validations.
- Maintain and troubleshoot analytical instruments.
- Communicate results and observations to the analytical, engineering, and process development teams through strong written and oral communication skills.
- Maintain GLP compliant lab records, lab notebooks, and procedures.
- Maintain a safety first approach to science.
- Think creatively, problem solve, and develop innovative solutions based on sound scientific analysis.
- Other duties as required.
Qualifications
PhD in Chemistry, Analytical Chemistry, or Bioanalytical Chemistry with 2-5 years of hands-on experience with analytical measurements and instrumental analysis in the biopharmaceutical or biotechnology industry,
Or
MS in Chemistry, Analytical Chemistry, or Bioanalytical Chemistry with 5-8 years of hands-on experience with analytical measurements and instrumental analysis in the biopharmaceutical or biotechnology industry.
Preferred Skills
- Experience with biopharmaceutical products, including the purification and characterization of proteins and monoclonal antibodies.
Required Skills
- Strong instrumental analysis experience, including, UV-Vis spectrometry, HPLC/UPLC, spectrofluorimetry, circular dichroism, microplate reader-based assays, and NMR.
- Experience with protein separation analysis and quantification, including, UV-Vis spectrometry, SEC, affinity chromatography, ion-exchange chromatography (IEX), hydrophobic interaction chromatography (HIC), BCA assay, Bradford assay, ELISA, gel electrophoresis, SDS-PAGE, Wester Blot, Isoelectric focusing, SPR, and ITC.
- Experience with analytical and bioanalytical methods development, qualification, and validation.
- Experience with writing SOPs.
- Experience working in a GLP/cGMP environment.
- Ability to design and execute controlled experiments with a strong attention to detail is essential.
- Driven self-starter with capability to work independently as well as on interdisciplinary teams with chemists, biochemist, biophysicists, biomedical engineers, chemical engineers, mechanical engineers, electrical engineers, controls engineers, analytical chemists, materials scientists, biologists, etc.
- Comfortable working on high risk technologies in a fast paced, dynamic start-up environment.
- Proficient computer skills including MS Office and statistical analysis software.
- Proficient oral and written communication skills.
Compensation
Mobius Biomedical offers a highly competitive salary commensurate with experience, Incentive Stock Options (ISOs), medical, dental, and vision benefits, short- and long-term disability, flexible spending account (FSA), and life insurance.
Position Type: Full-time
Position Location: Lowell, MA
Authorization to work in the U.S. is required.
Senior Chemical Engineer
Mobius Biomedical is an early-stage biopharmaceutical company that is focused on developing innovative, pathbreaking process technologies to dramatically reduce the costs of traditional biologics manufacturing.
Mobius Biomedical is searching for qualified, highly motivated engineers/scientists with experience in protein purification methods and process development to join our engineering team and serve as a Senior Chemical Engineer. This position will report directly to the Chief Scientific Officer.
Primary Responsibilities
- Work with the engineering team to design and prototype development of novel bioprocess equipment to enable reliable, cost-reductive downstream biopharmaceutical purification and processing.
- Perform computational modeling and theoretical calculations, requiring strong knowledge of liquid handling, fluidics, fluid flow, fluid dynamics, mass transfer and heat transfer.
- Work with the engineering and bioanalytical teams to design and perform appropriate experiments to test and evaluate equipment prototypes.
- Provide strong chemical engineering expertise in bioprocess technology design reviews.
- Communicate design concepts, troubleshooting ideas, results, and observations to the analytical, engineering, and process development teams through strong written and oral communication skills.
- Develop effective working relationships with both internal and external partners.
- Maintain GLP compliant lab records, lab notebooks, and procedures.
- Maintain a safety-first approach to science and engineering.
- Think creatively, problem solve, and develop innovative solutions based on sound scientific and engineering reasoning.
- Other duties as required.
Qualifications
PhD in Chemical Engineering, Biomedical Engineering, or related field with 2-5 years of relevant hands-on research experience with protein expression, protein purification, or separation science,
or
MS in Chemical Engineering, Biomedical Engineering, or related field with 5-8 years of relevant hands-on research experience with protein expression, protein purification, or separation science,
or
BS in Chemical Engineering, Biomedical Engineering, or related field with 8+ years of relevant hands-on research experience with protein expression, protein purification, or separation science.
Preferred Skills
- Experience with downstream biopharmaceutical processing and related equipment and instrumentation, including, centrifugation, depth filtration, affinity chromatography, ion-exchange chromatography, tangential flow filtration, ultrafiltration/diafiltration.
- Experience in the design and development of equipment for applications in life sciences.
Required Skills
- High level of proficiency in COMSOL for fluid flow applications, simulations, and modeling.
- Strong knowledge of applied science and engineering principles, including chemistry, physics, fluid dynamics, thermodynamics, mass transfer, and heat transfer.
- Strong working knowledge of and ability to select fluid control components and systems, including fittings, liquid handling lines, valves, gauges, sensors, and pumps.
- Experience and skill in selecting materials and components based on design criteria and biological/chemical process compatibility.
- Ability to design and execute controlled experiments with a strong attention to detail is essential.
- General knowledge in mechanical, electrical, and controls engineering disciplines.
- Driven self-starter with capability to work independently as well as on interdisciplinary teams with chemists, biochemist, biophysicists, biomedical engineers, chemical engineers, mechanical engineers, electrical engineers, controls engineers, analytical chemists, materials scientists, biologists, etc.
- Comfortable working on high risk technologies in a fast paced, dynamic start-up environment.
- Proficient computer skills including MS Office and statistical analysis software.
- Proficient oral and written communication skills.
Compensation
Mobius Biomedical offers a highly competitive salary commensurate with experience, Incentive Stock Options (ISOs), medical, dental, and vision benefits, short- and long-term disability, flexible spending account (FSA), and life insurance.
Position Type: Full-time
Position Location: Lowell, MA
Authorization to work in the U.S. is required.
Senior Mechanical Engineer
Mobius Biomedical is an early-stage biopharmaceutical company that is focused on developing innovative, pathbreaking process technologies to dramatically reduce the costs of traditional biologics manufacturing.
Mobius Biomedical is searching for qualified, highly motivated engineers/scientists with experience in protein purification methods and process development to join our engineering team and serve as a Senior Mechanical Engineer. This position will report directly to the Chief Scientific Officer.
Primary Responsibilities
- Work with the engineering team to design and prototype development of novel bioprocess equipment to enable reliable, cost-reductive downstream biopharmaceutical purification and processing.
- Lead the mechanical design and hands-on building, testing, troubleshooting, and design iterations of prototype equipment.
- Create and design parts, part assemblies, and equipment using SOLIDWORKS.
- Select appropriate components and materials based on design criteria.
- Work with the engineering and bioanalytical teams to design and perform appropriate experiments to test and evaluate equipment prototypes.
- Provide strong mechanical engineering expertise in bioprocess technology design reviews.
- Communicate design concepts, troubleshooting ideas, results, and observations to the analytical, engineering, and process development teams through strong written and oral communication skills.
- Develop effective working relationships with both internal and external partners.
- Maintain GLP compliant lab records, lab notebooks, and procedures.
- Maintain a safety first approach to science and engineering.
- Think creatively, problem solve, and develop innovative solutions based on sound scientific and engineering reasoning.
- Other duties as required.
Qualifications
PhD in Mechanical Engineering or related field with 2-5 years of relevant hands-on research experience with designing and prototyping equipment,
or
MS in Mechanical Engineering or related field with 5-8 years of relevant hands-on research experience with designing and prototyping equipment,
or
BS in Mechanical Engineering or related field with 8+ years of relevant hands-on research experience with designing and prototyping equipment
Preferred Skills
- Experience in the design and development of capital equipment for applications in life sciences.
- Experience with liquid handling and fluidics.
- Experience with downstream biopharmaceutical processing and related equipment, including centrifugation, depth filtration, affinity chromatography, ion-exchange chromatography, tangential flow filtration, ultrafiltration/diafiltration.
Required Skills
- High level of proficiency in SOLIDWORKS is essential.
- Strong hands-on mechanical and bench testing skills and ability to perform equipment design, assembly, testing, and troubleshooting.
- Strong knowledge of applied science and engineering principles, including physics, fluid dynamics, thermodynamics, mass transfer, and heat transfer.
- Strong knowledge of machining and fabrication techniques for prototypes and production equipment.
- Experience with geometric dimensioning and tolerancing.
- Strong working knowledge of and ability to select fluid control components and systems, including fittings, liquid handling lines, valves, gauges, sensors, and pumps.
- Experience and skill in selecting materials and components based on design criteria and biological/chemical process compatibility.
- Experience with interfacing directly with vendors, design firms, fabricating and machining service firms.
- Ability to design and execute controlled experiments with a strong attention to detail is essential.
- General knowledge in mechanical, electrical, and controls engineering disciplines.
- Driven self-starter with capability to work independently as well as on interdisciplinary teams with chemists, biochemist, biophysicists, biomedical engineers, chemical engineers, mechanical engineers, electrical engineers, controls engineers, analytical chemists, materials scientists, biologists, etc.
- Comfortable working on high risk technologies in a fast paced, dynamic start-up environment.
- Proficient computer skills including MS Office and statistical analysis software.
- Proficient oral and written communication skills.
Compensation
Mobius Biomedical offers a highly competitive salary commensurate with experience, Incentive Stock Options (ISOs), medical, dental, and vision benefits, short- and long-term disability, flexible spending account (FSA), and life insurance.
Position Type: Full-time
Position Location: Lowell, MA
Authorization to work in the U.S. is required.